The role of sidedness, EGFR gene copy number (GCN) and EGFR promoter methylation in RAS/BRAF wild type (WT) colorectal cancer (CRC) patients receiving irinotecan/cetuximab.
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DOI: 10.1200/jco.2017.35.4_suppl.628
Abstract: 628Background: Data from randomized trials suggested that tumour sidedness could represent a prognostic and predictive factor in CRC patients. Distinctive molecular and clinical features are related to tumour sidedness, however their predictive role has not… read more here.
Keywords: sidedness; egfr promoter; promoter methylation; crc patients ... See more keywords