A drug discovery platform to identify compounds that inhibit EGFR triple mutants
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DOI: 10.1038/s41589-020-0484-2
Abstract: Receptor tyrosine kinases (RTKs) are transmembrane receptors of great clinical interest due to their role in disease. Historically, therapeutics targeting RTKs have been identified using in vitro kinase assays. Due to frequent development of drug… read more here.
Keywords: compounds inhibit; drug; drug screening; platform ... See more keywords