Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14092065
Abstract: Seasonal H3N2 influenza evolves rapidly, leading to an extremely poor vaccine efficacy. Substitutions employed during vaccine production using embryonated eggs (i.e., egg passage adaptation) contribute to the poor vaccine efficacy (VE), but the evolutionary mechanism… read more here.
Keywords: h3n2 influenza; virus; fitness landscape; passage ... See more keywords