Early-Onset Glaucoma in egl1 Mice Homozygous for Pitx2 Mutation
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DOI: 10.3390/biomedicines10030516
Abstract: Mutations in PITX2 cause Axenfeld–Rieger syndrome, with congenital glaucoma as an ocular feature. The egl1 mouse strain carries a chemically induced Pitx2 mutation and develops early-onset glaucoma. In this study, we characterized the glaucomatous features… read more here.
Keywords: glaucoma; early onset; pitx2 mutation; egl1 mice ... See more keywords