Calming egress of inflammatory monocytes and related septic shock by therapeutic CCR2 silencing using macrophage-derived extracellular vesicles.
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DOI: 10.1039/d1nr06922e
Abstract: Uncontrolled inflammation, featuring the aggravated mobilization of Ly6Chigh inflammatory monocytes (Mos), may cause high morbidity and mortality in the pathogenesis of sepsis-associated immune disorders. Inspired by the similar membrane protein profile of extracellular vehicles (EVs)… read more here.
Keywords: inflammatory monocytes; ccr2; inflammatory; egress inflammatory ... See more keywords