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   Articles with "egt" as a keyword



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Ergothioneine attenuates varicocele‐induced testicular damage by upregulating HSP90AA1 in rats

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recommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23301

Abstract: This study investigates the therapeutic effect and the underlying mechanisms of ergothioneine (EGT) on the testicular damage caused by varicocele (VC) in vivo, in vitro, and in silico. This preclinical study combines a series of… read more here.

Keywords: egt; pharmacology; testicular damage; vivo vitro ... See more keywords

Biosynthesis of ergothioneine: current state, achievements, and perspectives

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recommendations! Published in 2025 at "Applied Microbiology and Biotechnology"

DOI: 10.1007/s00253-025-13476-4

Abstract: Ergothioneine (EGT) is a derivative of the amino acid L-histidine that is well known for its strong antioxidant properties. Recent studies on the functional characterization of EGT in both in vivo and in vitro systems… read more here.

Keywords: current state; egt; biosynthesis ergothioneine; ergothioneine current ... See more keywords

Efficient Synthesis of Food-Derived Antioxidant l-Ergothioneine by Engineered Corynebacterium glutamicum.

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recommendations! Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.1c07541

Abstract: l-Ergothioneine (EGT) is a strong antioxidant used in industry, and it is commonly extracted from mushrooms; however, its production is limited. As an alternative, we developed metabolically engineered Corynebacterium glutamicum with reinforced sulfur assimilation and… read more here.

Keywords: corynebacterium glutamicum; egt; glutamicum; ergothioneine ... See more keywords

Protective role of ergothioneine isolated from Pleurotus ostreatus against dextran sulfate sodium-induced ulcerative colitis in rat model.

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recommendations! Published in 2021 at "Journal of food science"

DOI: 10.1111/1750-3841.15982

Abstract: The well-acknowledged sulfur-containing amino acid ergothioneine (EGT), which is usually perceived to be produced from fungi, cyanobacteria, and mushrooms, has been increasingly demonstrated as a diet-derived antioxidant with therapeutic potential. However, little is known regarding… read more here.

Keywords: pleurotus ostreatus; ulcerative colitis; dextran sulfate; egt ... See more keywords

Oxidized Forms of Ergothioneine Are Substrates for Mammalian Thioredoxin Reductase

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recommendations! Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11020185

Abstract: Ergothioneine (EGT) is a sulfur-containing amino acid analog that is biosynthesized in fungi and bacteria, accumulated in plants, and ingested by humans where it is concentrated in tissues under oxidative stress. While the physiological function… read more here.

Keywords: thioredoxin reductase; mammalian thioredoxin; egt; oxidized forms ... See more keywords