Ergothioneine attenuates varicocele‐induced testicular damage by upregulating HSP90AA1 in rats
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23301
Abstract: This study investigates the therapeutic effect and the underlying mechanisms of ergothioneine (EGT) on the testicular damage caused by varicocele (VC) in vivo, in vitro, and in silico. This preclinical study combines a series of… read more here.
Keywords: egt; pharmacology; testicular damage; vivo vitro ... See more keywords
Efficient Synthesis of Food-Derived Antioxidant l-Ergothioneine by Engineered Corynebacterium glutamicum.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c07541
Abstract: l-Ergothioneine (EGT) is a strong antioxidant used in industry, and it is commonly extracted from mushrooms; however, its production is limited. As an alternative, we developed metabolically engineered Corynebacterium glutamicum with reinforced sulfur assimilation and… read more here.
Keywords: corynebacterium glutamicum; egt; glutamicum; ergothioneine ... See more keywords
Protective role of ergothioneine isolated from Pleurotus ostreatus against dextran sulfate sodium-induced ulcerative colitis in rat model.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of food science"
DOI: 10.1111/1750-3841.15982
Abstract: The well-acknowledged sulfur-containing amino acid ergothioneine (EGT), which is usually perceived to be produced from fungi, cyanobacteria, and mushrooms, has been increasingly demonstrated as a diet-derived antioxidant with therapeutic potential. However, little is known regarding… read more here.
Keywords: pleurotus ostreatus; ulcerative colitis; dextran sulfate; egt ... See more keywords
Oxidized Forms of Ergothioneine Are Substrates for Mammalian Thioredoxin Reductase
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11020185
Abstract: Ergothioneine (EGT) is a sulfur-containing amino acid analog that is biosynthesized in fungi and bacteria, accumulated in plants, and ingested by humans where it is concentrated in tissues under oxidative stress. While the physiological function… read more here.
Keywords: thioredoxin reductase; mammalian thioredoxin; egt; oxidized forms ... See more keywords