Implication of HMOX1 and CCR5 genotypes on clinical phenotype of Egyptian patients with sickle cell anemia
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Hematology"
DOI: 10.1007/s00277-019-03697-9
Abstract: Sickle cell disease (SCD) is a relatively common inherited hemolytic anemia among individuals of African descent. Genetic factors might clarify clinical diversity of the disease and variations in treatment response. Some researchers investigated heme oxygenase-1… read more here.
Keywords: ccr5 genotypes; disease; ccr5; sickle cell ... See more keywords
Investigation of the relationship between CTLA4 and the tumor suppressor RASSF1A and the possible mediating role of STAT4 in a cohort of Egyptian patients infected with hepatitis C virus with and without hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of virology"
DOI: 10.1007/s00705-021-04981-8
Abstract: The Ras association domain family 1 isoform A (RASSF1A), cytotoxic T lymphocyte antigen 4 (CTLA-4), and signal transducer and activator of transcription 4 (STAT4) genes play a role in regulating the cell cycle, apoptosis, and… read more here.
Keywords: hepatocellular carcinoma; stat4; hcv mediated; hepatitis virus ... See more keywords
Peripapillary retinal nerve fiber layer and ganglion cell complex degeneration in Egyptian patients with bipolar disorder
Sign Up to like & getrecommendations! Published in 2019 at "Eye"
DOI: 10.1038/s41433-019-0403-5
Abstract: PurposeTo determine if changes in OCT parameters including peripapillary RNFL thickness and GCC thickness in Egyptian patients with bipolar disorder exist, and to correlate them with disease severity and clinical characteristics.MethodsA case–control study conducted on… read more here.
Keywords: peripapillary retinal; patients bipolar; retinal nerve; bipolar disorder ... See more keywords
RNA protein kinase SNP at −226 C
Sign Up to like & getrecommendations! Published in 2019 at "Immunological Investigations"
DOI: 10.1080/08820139.2018.1493496
Abstract: ABSTRACT Background: RNA-dependant protein kinase R (PKR) is a primary mediator in the defence mechanism of interferon against viral replication and pathogenesis during Hepatitis C virus (HCV) infection. In the present study, we have examined… read more here.
Keywords: hcv; hcv infection; snp 226; protein kinase ... See more keywords
Assessment of the Prevalence of Non-Organ-Specific Autoantibodies in Egyptian Patients with HCV
Sign Up to like & getrecommendations! Published in 2019 at "Immunological Investigations"
DOI: 10.1080/08820139.2019.1699108
Abstract: ABSTRACT The relation between non-organ specific autoantibodies (NOSA) and hepatitis C virus (HCV) infection has been investigated within different communities resulting in different prevalence rates and patterns. The purpose of this study was to investigate… read more here.
Keywords: organ specific; specific autoantibodies; non organ; egyptian patients ... See more keywords
Genetic polymorphisms of IL-23R (rs7517847) and LEP (rs7799039) among Egyptian patients with hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Physiology and Biochemistry"
DOI: 10.1080/13813455.2017.1320680
Abstract: Abstract Background: Genetic polymorphisms of IL-23 R (rs7517847) and LEP (rs7799039) have been stated to be associated with various types of human cancers. The purpose of this work is to test the association of these genetic… read more here.
Keywords: among egyptian; genetic polymorphisms; lep rs7799039; rs7517847 lep ... See more keywords
Multiplex ligation-dependent probe amplification versus fluorescent in situ hybridization for screening RB1 copy number variations in Egyptian patients with retinoblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Ophthalmic Genetics"
DOI: 10.1080/13816810.2022.2116650
Abstract: ABSTRACT Background Retinoblastoma (RB) is the most common primary intraocular malignant tumor in children. RB is mostly caused by biallelic mutations in RB1 and occurs in hereditary and non-hereditary forms according to the “two-hit” theory.… read more here.
Keywords: number variations; multiplex ligation; copy number; rb1 copy ... See more keywords
Molecular Patterns of MEFV Gene Mutations in Egyptian Patients with Familial Mediterranean Fever: A Retrospective Cohort Study
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Inflammation"
DOI: 10.1155/2019/2578760
Abstract: Background Familial Mediterranean Fever (FMF) is a hereditary autosomal recessive disease which is mainly seen in the Turks, Armenians, Arabs, and Jews. It is characterized by recurrent episodes of fever, polyserositis, and rash. MEFV gene,… read more here.
Keywords: gene mutations; mefv gene; familial mediterranean; gene ... See more keywords
Rates and profile of victimization in a sample of Egyptian patients with major mental illness
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Social Psychiatry"
DOI: 10.1177/0020764019831315
Abstract: Background: Patients with major mental illness have an increased risk of victimization. Nevertheless, this topic was not thoroughly studied in Egyptian patients with major mental illness. Objectives: The objectives of this study are to investigate… read more here.
Keywords: victimization; major mental; patients major; mental illness ... See more keywords
Interleukin-18 and interferon-γ single nucleotide polymorphisms in Egyptian patients with tuberculosis
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0244949
Abstract: Background Interleukin-18 (IL-18) and interferon-γ (IFN-γ) are cytokines of crucial role in inflammation and immune reactions. There is a growing evidence supporting important roles for IL-18 and IFN γ in tuberculosis (TB) infection and anti-tuberculosis… read more here.
Keywords: risk; infection; inf 874; tuberculosis ... See more keywords
Impact of Obesity and Its Associated Comorbid Conditions on COVID-19 Presentation
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s287779
Abstract: Background There is great variability in clinical presentation of COVID-19 worldwide. The current study evaluated the impact of obesity and its related complications on the course of COVID-19 in Egyptian patients. Methods We included 230… read more here.
Keywords: egyptian patients; obesity; presentation; obesity associated ... See more keywords