MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites
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DOI: 10.1038/s41598-018-29239-3
Abstract: Chromatin dynamics mediated by post-translational modifications play a crucial role in cellular response to genotoxic stress for the maintenance of genome integrity. MDC1 is a pivotal chromatin adaptor in DNA damage response (DDR) and its… read more here.
Keywords: ehmt1 ehmt2; dna damage; methylation; accumulation ... See more keywords