Structural analysis of EhPSP in complex with 3-phosphoglyceric acid from Entamoeba histolytica reveals a basis for its lack of phosphoglycerate mutase activity.
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DOI: 10.1016/j.ijbiomac.2021.02.153
Abstract: Entamoeba histolytica phosphoserine phosphatase (EhPSP), a regulatory enzyme in the serine biosynthetic pathway, is also a structural homolog of cofactor-dependent phosphoglycerate mutase (dPGM). However, despite sharing many of its catalytic residues with dPGM, EhPSP displays… read more here.
Keywords: ehpsp; ehpsp complex; phosphoglycerate mutase; entamoeba histolytica ... See more keywords