Articles with "ehrlich ascites" as a keyword



Ameliorative effects of vitamin B17 on the kidney against Ehrlich ascites carcinoma induced renal toxicity in mice

Sign Up to like & get
recommendations!
Published in 2019 at "Environmental Toxicology"

DOI: 10.1002/tox.22888

Abstract: Cancer is the major cause of death and many factors that lead to its occurrences, such as environmental pollution and pesticides and other factors. Ehrlich carcinoma development depends on many things associated with the environment,… read more here.

Keywords: ascites carcinoma; group; effects vitamin; vitamin b17 ... See more keywords

The study of the calpain and caspase-1 expression in ultrastructural dynamics of Ehrlich ascites carcinoma necrosis.

Sign Up to like & get
recommendations!
Published in 2018 at "Gene"

DOI: 10.1016/j.gene.2018.03.012

Abstract: An expression of calpain and caspase-1 as well as the concomitant ultrastructural alterations were investigated during necrosis of the mouse Ehrlich ascites carcinoma. The calpain expression was registered at 0 h and 1 h although caspase-1 did… read more here.

Keywords: ascites carcinoma; calpain; calpain caspase; expression ... See more keywords

Antitumour, acute toxicity and molecular modeling studies of 4-(pyridin-4-yl)-6-(thiophen-2-yl) pyrimidin-2(1H)-one against Ehrlich ascites carcinoma and sarcoma-180

Sign Up to like & get
recommendations!
Published in 2018 at "Heliyon"

DOI: 10.1016/j.heliyon.2018.e00661

Abstract: In an effort to discover an effective and selective antitumour agent, synthesis and anti-cancer potential of 4-(pyridin-4-yl)-6-(thiophen-2-yl) pyrimidin-2(1H)-one (SK-25), which has been reported earlier by us with significant cytotoxicity towards MiaPaCa-2 malignant cells, with an… read more here.

Keywords: ascites carcinoma; sarcoma 180; pyridin thiophen; thiophen pyrimidin ... See more keywords

LQFM030 reduced Ehrlich ascites tumor cell proliferation and VEGF levels

Sign Up to like & get
recommendations!
Published in 2018 at "Life Sciences"

DOI: 10.1016/j.lfs.2017.12.029

Abstract: Aims: This study reports the biological properties of LQFM030 in vivo, a molecular simplification of the compound nutlin‐1. Main methods: Ehrlich ascites tumor (EAT)‐bearing mice were treated intraperitoneally with LQFM030 (50, 75 or 150 mg/kg)… read more here.

Keywords: vegf; cell proliferation; tumor cell; ehrlich ascites ... See more keywords

Anchoring of Nanocomposites Based on Novel Metal Nanocomplexes/Nanocarbonaceous Surfaces and Assessing Their In Vivo Anticancer Effects on Ehrlich Ascites Tumor

Sign Up to like & get
recommendations!
Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c05631

Abstract: Nanotechnology is the study of materials’ unique properties at the nanoscale. Nanomedicine is the application of nanotechnology in medicine, which has been utilized to treat some common diseases, such as cancer. The aim of the… read more here.

Keywords: effects ehrlich; nanotechnology; group; anticancer effects ... See more keywords

Vitamin B17 alleviates Sorafenib-induced cardiotoxicity in Ehrlich Ascites Carcinoma mice via modulation of inflammatory and fibrotic pathways

Sign Up to like & get
recommendations!
Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-11643-1

Abstract: Chemotherapy-induced cardiotoxicity remains a major clinical concern, with Sorafenib (Sor) being among the agents associated with adverse cardiac effects. Vitamin B17 (VB17), known for its antioxidant and anti-inflammatory properties, has shown promise in mitigating cardiovascular… read more here.

Keywords: ascites carcinoma; combination; ehrlich ascites; induced cardiotoxicity ... See more keywords

Regression of murine Ehrlich ascites carcinoma using synthesized cobalt complex.

Sign Up to like & get
recommendations!
Published in 2017 at "MedChemComm"

DOI: 10.1039/c6md00618c

Abstract: Cisplatin as a chief chemotherapy has nephro-toxicity and so we have tried to develop a novel antitumor drug based on a combination of cobalt metal ion with an organic moiety. The antitumor activity of the… read more here.

Keywords: ascites carcinoma; cobalt complex; cobalt; murine ehrlich ... See more keywords

Antitumor effectiveness and mechanism of action of Ru(II)/amino acid/diphosphine complexes in the peritoneal carcinomatosis progression

Sign Up to like & get
recommendations!
Published in 2017 at "Tumor Biology"

DOI: 10.1177/1010428317695933

Abstract: Peritoneal carcinomatosis is considered as a potentially lethal clinical condition, and the therapeutic options are limited. The antitumor effectiveness of the [Ru(l-Met)(bipy)(dppb)]PF6 (1) and the [Ru(l-Trp)(bipy)(dppb)]PF6 (2) complexes were evaluated in the peritoneal carcinomatosis model,… read more here.

Keywords: ascites carcinoma; amino acid; ehrlich ascites; mechanism action ... See more keywords

Suppression of Ehrlich ascites tumor cell proliferation via G1 arrest induced by dietary nucleic acid-derived nucleosides

Sign Up to like & get
recommendations!
Published in 2024 at "PLOS ONE"

DOI: 10.1371/journal.pone.0305775

Abstract: The nucleic acids found in food play a crucial role in maintaining various bodily functions. This study investigated the potential anticancer effects of dietary nucleic acids, an area that is still not fully understood. By… read more here.

Keywords: nucleic acid; ehrlich ascites; dietary nucleic; ascites tumor ... See more keywords

2', 4'-dihydroxy-3, 4-methylenedioxychalcone Activate Mitochondrial Apoptosis of Ehrlich Ascites Carcinoma Cells

Sign Up to like & get
recommendations!
Published in 2020 at "Current Drug Therapy"

DOI: 10.2174/1574885514666191211122437

Abstract: Background: Development of effective cancer-chemotherapy is the most challenging field due to toxicity of chemo-agents. Objective: As chalcone has been known to have pharmacological applications, here we aimed to synthesized three chalcone derivatives, 2',4'-dihydroxy-3,4-methylenedioxychalcone (C1),… read more here.

Keywords: ascites carcinoma; apoptosis; eac cells; dihydroxy methylenedioxychalcone ... See more keywords

Silymarin nanoformulation as potential anticancer agent in experimental Ehrlich ascites carcinoma-bearing animals.

Sign Up to like & get
recommendations!
Published in 2018 at "Nanomedicine"

DOI: 10.2217/nnm-2017-0394

Abstract: AIM This study aimed to evaluate, for the first time the potential use of a safe biocompatible nanoformulation of silymarin (SM) as antitumor agent and to provide its mechanism of action compared with native SM.… read more here.

Keywords: ascites carcinoma; agent; nanoformulation potential; ehrlich ascites ... See more keywords