Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin‐2 via the PERK‐eIF2&agr;‐ATF4 pathway
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.05.026
Abstract: Abstract Nonalcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, has emerged as one of the most common causes of chronic liver disease in developed countries over the last decade. NAFLD comprises… read more here.
Keywords: hepatic steatosis; eif2 agr; expression; carbon monoxide ... See more keywords
The regulation of cellular apoptosis by the ROS‐triggered PERK/EIF2&agr;/chop pathway plays a vital role in bisphenol A‐induced male reproductive toxicity
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DOI: 10.1016/j.taap.2016.11.013
Abstract: Abstract Bisphenol A (2,2‐bis(4‐hydroxyphenyl)propane, BPA) is ubiquitous in the environment, wildlife, and humans. Evidence from past studies suggests that BPA is associated with decreased semen quality. However, the molecular basis for the adverse effect of… read more here.
Keywords: bpa; perk eif2; agr chop; eif2 agr ... See more keywords