Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes
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DOI: 10.7554/elife.24542
Abstract: Phosphorylation of eIF2α controls translation initiation by restricting the levels of active eIF2-GTP/Met-tRNAi ternary complexes (TC). This modulates the expression of all eukaryotic mRNAs and contributes to the cellular integrated stress response. Key to controlling… read more here.
Keywords: ternary complexes; eif2; eif2 gtp; translation ... See more keywords