Abstract A13: eIF4a paralogue switching drives opposing phenotypes in cancer by specific reprogramming of gene expression
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.transcontrol16-a13
Abstract: Abstracts: AACR Special Conference on Translational Control of Cancer: A New Frontier in Cancer Biology and Therapy; October 27-30, 2016; San Francisco, CA Aims: We aim to unravel the divergent roles of the paralogs of… read more here.
Keywords: expression; translation; biology; cancer ... See more keywords
BLF1 Affects ATP Hydrolysis Catalyzed by Native and Mutated eIF4A1 and eIF4A2 Proteins
Sign Up to like & getrecommendations! Published in 2025 at "Toxins"
DOI: 10.3390/toxins17050232
Abstract: Burkholderia lethal factor 1 (BLF1), a toxin derived from Burkholderia pseudomallei, reacts with eukaryotic initiation factor (eIF) 4A to inhibit protein synthesis. eIF4A1 and eIF4A2 are involved in translation initiation and share over 90% sequence… read more here.
Keywords: blf1 affects; eif4a1 eif4a2; atp hydrolysis; eif4a isoforms ... See more keywords