Articles with "eif4a2" as a keyword



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Effect of knockdown of eukaryotic initiation factor 4A2 (eIF4A2) on growth, metastasis, and oxaliplatin sensitivity in colorectal cancer.

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Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.15_suppl.e15658

Abstract: e15658Background: Our previous study found that eIF4A2 was highly expressed in colorectal cancer and high eIF4A2 expression predicted poor prognosis, which was reported in ASCO GI 2018. However, th... read more here.

Keywords: eif4a2; effect knockdown; eukaryotic initiation; colorectal cancer ... See more keywords

BLF1 Affects ATP Hydrolysis Catalyzed by Native and Mutated eIF4A1 and eIF4A2 Proteins

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Published in 2025 at "Toxins"

DOI: 10.3390/toxins17050232

Abstract: Burkholderia lethal factor 1 (BLF1), a toxin derived from Burkholderia pseudomallei, reacts with eukaryotic initiation factor (eIF) 4A to inhibit protein synthesis. eIF4A1 and eIF4A2 are involved in translation initiation and share over 90% sequence… read more here.

Keywords: blf1 affects; eif4a1 eif4a2; atp hydrolysis; eif4a isoforms ... See more keywords