The domains of yeast eIF4G, eIF4E and the cap fine-tune eIF4A activities through an intricate network of stimulatory and inhibitory effects
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DOI: 10.1093/nar/gkac437
Abstract: Abstract Translation initiation in eukaryotes starts with the recognition of the mRNA 5′-cap by eIF4F, a hetero-trimeric complex of eIF4E, the cap-binding protein, eIF4A, a DEAD-box helicase, and eIF4G, a scaffold protein. eIF4G comprises eIF4E-… read more here.
Keywords: eif4e cap; stimulatory inhibitory; network stimulatory; cap ... See more keywords