Loss of EIF4G2 mediates aggressiveness in distinct human endometrial cancer subpopulations with poor survival outcome in patients
Sign Up to like & getrecommendations! Published in 2024 at "Oncogene"
DOI: 10.1038/s41388-024-02981-x
Abstract: The non-canonical translation initiation factor EIF4G2 plays essential roles in cellular stress responses via translation of selective mRNA cohorts. Currently there is limited and conflicting information regarding its involvement in cancer development and progression. Here… read more here.
Keywords: cancer; eif4g2; eif4g2 mediates; loss eif4g2 ... See more keywords
Long non-coding RNA (LncRNA) SNHG7/ Eukaryotic translation initiation factor 4 gamma 2 (EIF4G2) involves in the malignant events of ovarian cancer cells with paclitaxel resistant.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1999555
Abstract: LncRNA SNHG7 shows a strong relationship with malignant behavior of cancer cells and poor clinical outcome in cancer. The resistance of ovarian cancer for Paclitaxel seriously limits the clinical efficacy in chemotherapy for ovarian cancer… read more here.
Keywords: ovarian cancer; eif4g2; lncrna snhg7; cancer cells ... See more keywords
Specific mechanisms of translation initiation in higher eukaryotes: the eIF4G2 story
Sign Up to like & getrecommendations! Published in 2022 at "RNA"
DOI: 10.1261/rna.079462.122
Abstract: The eukaryotic initiation factor 4G2 (eIF4G2, DAP5, Nat1, p97) was discovered in 1997. Over the past two decades, dozens of papers have presented contradictory data on eIF4G2 function. Since its identification, eIF4G2 has been assumed… read more here.
Keywords: eif4g2; specific mechanisms; translation initiation; higher eukaryotes ... See more keywords