O-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response
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DOI: 10.1038/s41589-018-0120-6
Abstract: Heat shock response (HSR) is an ancient signaling pathway leading to thermoprotection of nearly all living organisms. Emerging evidence suggests that intracellular O-linked β-N-acetylglucosamine (O-GlcNAc) serves as a molecular ‘thermometer’ by reporting ambient temperature fluctuations.… read more here.
Keywords: glcnac modification; eif4gi; heat shock; stress ... See more keywords