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Variations in the Frequencies of Polymorphisms in the CYP450s Genes in Eight Major Ethnicities of Iran: A Review of the Human Data

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Published in 2022 at "Journal of Personalized Medicine"

DOI: 10.3390/jpm12111848

Abstract: Genetic polymorphisms in cytochrome P450 genes can cause variation in metabolism. Thus, single nucleotide variants significantly impact drug pharmacokinetics, toxicity factors, and efficacy and safety of medicines. The distribution of CYP450 alleles varies drastically across… read more here.

Keywords: frequencies polymorphisms; variations frequencies; major ethnicities; ethnicities iran ... See more keywords