Starch nanocapsules containing a novel neutrophil elastase inhibitor with improved pharmaceutical performance
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.01.011
Abstract: Graphical abstract Figure. No caption available. HighlightsER143‐loaded StNC proved as a strategy to improve ER143 pharmaceutical performance.ER143‐loaded StNC showed an improved anti‐inflammatory effect.A QbD approach was successfully applied to obtain ER143‐loaded StNC. &NA; Psoriasis and… read more here.
Keywords: pharmaceutical performance; elastase inhibitor; neutrophil elastase; improved pharmaceutical ... See more keywords
Elastase Inhibitor Cyclotheonellazole A: Total Synthesis and In Vivo Biological Evaluation for Acute Lung Injury
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.1c01583
Abstract: Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is one of the most common complications in COVID-19. Elastase has been recognized as an important target to prevent ALI/ARDS in the patient of COVID-19. Cyclotheonellazole A (CTL-A)… read more here.
Keywords: acute lung; elastase inhibitor; elastase; lung injury ... See more keywords