Three dimensional microstructural network of elastin, collagen, and cells in Achilles tendons
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23240
Abstract: Similar to most biological tissues, the biomechanical, and functional characteristics of the Achilles tendon are closely related to its composition and microstructure. It is commonly reported that type I collagen is the predominant component of… read more here.
Keywords: collagen; achilles tendons; collagen cells; microstructural network ... See more keywords
Fabrication and Characterization of Recombinant Silk-Elastin-Like-Protein (SELP) Fiber.
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800265
Abstract: Silk-elastin-like-protein polymers (SELPs) are genetically engineered recombinant protein sequences consisting of repeating units of silk-like and elastin-like blocks. By combining these entities, it is shown that both the characteristic strength of silk and the temperature-dependent… read more here.
Keywords: silk elastin; protein; selp; elastin like ... See more keywords
Use of versican variant V3 and versican antisense expression to engineer cultured human skin containing increased content of insoluble elastin
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1913
Abstract: Skin substitutes for repair of dermal wounds are deficient in functional elastic fibres. We report that the content of insoluble elastin in the dermis of cultured human skin can be increased though the use of… read more here.
Keywords: insoluble elastin; versican variant; skin; expression ... See more keywords
Fascicular elastin within tendon contributes to the magnitude and modulus gradient of the elastic stress response across tendon type and species.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2022.03.025
Abstract: Elastin, the main component of elastic fibers, has been demonstrated to significantly influence tendon mechanics using both elastin degradation studies and elastinopathic mouse models. However, it remains unclear how prior results differ between species and… read more here.
Keywords: response; tendon; stress; elastin ... See more keywords
The mineralization process of insoluble elastin fibrillar structures: Ionic environment vs degradation.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.01.250
Abstract: Despite its long half-life and physiological role, elastin undergoes irreversible changes (i.e elastolysis and/or calcification) impairing resilience of soft connective tissues. At present, it is still undefined: 1) to which extent elastin fibers have to… read more here.
Keywords: insoluble elastin; ionic environment; mineralization process; mineralization ... See more keywords
Evaluation of a biomimetic 3D substrate based on the Human Elastin-like Polypeptides (HELPs) model system for elastolytic activity detection.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2017.06.006
Abstract: Elastin is a fibrous protein that confers elasticity to tissues such as skin, arteries and lung. It is extensively cross-linked, highly hydrophobic and insoluble. Nevertheless, elastin can be hydrolysed by bacterial proteases in infectious diseases,… read more here.
Keywords: evaluation; activity detection; elastolytic activity; activity ... See more keywords
Understanding the viscoelastic behavior of arterial elastin in glucose via relaxation time distribution spectrum.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2017.10.023
Abstract: Elastin is a critical extracellular matrix protein that provides many biological tissues with resilience. In elastic arteries such as aorta, elasticity is crucial for energy storage and transmission of the pulsatile blood flow. As one… read more here.
Keywords: relaxation time; stress relaxation; relaxation; time distribution ... See more keywords
Comparison of water, hydroxyproline, uronic acid and elastin contents of bovine knee ligaments and patellar tendon and their relationships with biomechanical properties.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2020.103639
Abstract: Mechanical material properties of ligaments originate from their biochemical composition and structural organization. However, it is not yet fully elucidated how biochemical contents vary between knee ligaments and patellar tendon (PT) and how they relate… read more here.
Keywords: uronic acid; content; elastin contents; knee ligaments ... See more keywords
Copper as the most likely pathogenic divergence factor between lung fibrosis and emphysema.
Sign Up to like & getrecommendations! Published in 2018 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2018.08.003
Abstract: Although fibrosis and emphysema are in many ways on opposite ends of the pulmonary parenchymal disease spectrum, they seem to share common pathomechanistic steps. This is illustrated by the coexistence of both entities in lungs… read more here.
Keywords: fibrosis; fibrosis emphysema; emphysema; factor ... See more keywords
Synthesis of desmosine-containing cyclic peptide for the possible elucidation of elastin crosslinking structure
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.05.045
Abstract: Abstract Elastin is a vital extracellular matrix protein, which is known for providing elasticity in numerous tissues. It is formed by the self-assembly and subsequent crosslinking of elastin precursor, tropoelastin. Two tetrafunctional, pyridinium-based amino acids… read more here.
Keywords: elucidation; elucidation elastin; cyclic peptide; containing cyclic ... See more keywords
Elastin-inspired supramolecular hydrogels: a multifaceted extracellular matrix protein in biomedical engineering.
Sign Up to like & getrecommendations! Published in 2021 at "Soft matter"
DOI: 10.1039/d0sm02202k
Abstract: The phenomenal advancement in regenerative medicines has led to the development of bioinspired materials to fabricate a biomimetic artificial extracellular matrix (ECM) to support cellular survival, proliferation, and differentiation. Researchers have diligently developed protein polymers… read more here.
Keywords: protein; engineering; extracellular matrix; elastin inspired ... See more keywords