Specific elastin degradation products are associated with poor outcome in the ECLIPSE COPD cohort
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-40785-2
Abstract: Chronic obstructive pulmonary disease (COPD) is characterized by a slow heterogeneous progression. Therefore, improved biomarkers that can accurately identify patients with the highest likelihood of progression and therefore the ability to benefit from a given… read more here.
Keywords: specific elastin; copd; cohort; degradation products ... See more keywords
Is cardiovascular disease in patients with diabetes associated with serum levels of MMP-2, LOX, and the elastin degradation products ELM and ELM-2?
Sign Up to like & getrecommendations! Published in 2017 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2017.1346822
Abstract: Abstract Background: Diabetes mellitus type 2 (T2DM) is a significant risk factor for the development of cardiovascular diseases (CVDs). In a previous microarray study of internal mammary arteries from patients with and without T2DM, we… read more here.
Keywords: lox elastin; serum; degradation products; elastin degradation ... See more keywords
Elastases and elastokines: elastin degradation and its significance in health and disease
Sign Up to like & getrecommendations! Published in 2020 at "Critical Reviews in Biochemistry and Molecular Biology"
DOI: 10.1080/10409238.2020.1768208
Abstract: Abstract Elastin is an important protein of the extracellular matrix of higher vertebrates, which confers elasticity and resilience to various tissues and organs including lungs, skin, large blood vessels and ligaments. Owing to its unique… read more here.
Keywords: degradation; elastases elastokines; disease; elastokines elastin ... See more keywords
Blackcurrant (Ribes nigrum L.) Extract Exerts Potential Vasculoprotective Effects in Ovariectomized Rats, Including Prevention of Elastin Degradation and Pathological Vascular Remodeling
Sign Up to like & getrecommendations! Published in 2021 at "Nutrients"
DOI: 10.3390/nu13020560
Abstract: Estrogen exerts cardioprotective effects in menopausal women. Phytoestrogens are plant-derived substances exhibiting estrogenic activity that could beneficially affect vascular health. We previously demonstrated that blackcurrant (Ribes nigrum L.) extract (BCE) treatment exerted beneficial effects on… read more here.
Keywords: elastin degradation; bce; pathological vascular; vascular remodeling ... See more keywords