Covalently adaptable elastin-like protein - hyaluronic acid (ELP - HA) hybrid hydrogels with secondary thermoresponsive crosslinking for injectable stem cell delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced functional materials"
DOI: 10.1002/adfm.201605609
Abstract: Shear-thinning, self-healing hydrogels are promising vehicles for therapeutic cargo delivery due to their ability to be injected using minimally invasive surgical procedures. We present an injectable hydrogel using a novel combination of dynamic covalent crosslinking… read more here.
Keywords: like protein; elp; elastin like; hyaluronic acid ... See more keywords
Functionalized Collagen/Elastin‐like Polypeptide Hydrogels for Craniofacial Bone Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202477
Abstract: Critical‐sized cranial bone defects fail to re‐ossify and require the surgical intervention of cranioplasty. To achieve superior bone healing in such cases, a hydrogel consisting of an interpenetrating network of collagen and elastin‐like polypeptide to… read more here.
Keywords: like polypeptide; collagen elastin; bone; elastin like ... See more keywords
Effect of amino acid composition of elastin-like polypeptide nanoparticles on nonspecific protein adsorption, macrophage cell viability and phagocytosis.
Sign Up to like & getrecommendations! Published in 2021 at "Biopolymers"
DOI: 10.1002/bip.23468
Abstract: Development of elastin-like polypeptide (ELP) biomaterials is widespread, but information critical for clinical deployment is limited, with biocompatibility studies focused on a narrow cross-section of ELP sequences. Macrophages can impair biomaterial systems by degrading or… read more here.
Keywords: elp nps; amino acid; elp; elastin like ... See more keywords
Flexible customization of the self‐assembling abilities of short elastin‐like peptide Fn analogs by substituting N‐terminal amino acids
Sign Up to like & getrecommendations! Published in 2022 at "Biopolymers"
DOI: 10.1002/bip.23521
Abstract: Elastin‐like peptides (ELPs) are thermoresponsive biopolymers inspired by the characteristic repetitive sequences of natural elastin. As ELPs exhibit temperature‐dependent reversible self‐assembly, they are expected to be biocompatible thermoresponsive materials for drug delivery carriers. One of… read more here.
Keywords: self assembling; amino acids; amino; elastin like ... See more keywords
Synthesis of single‐chain antibody fragment fused to the elastin‐like polypeptide in Nicotiana benthamiana and its application in affinity precipitation of difficult to produce proteins
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28158
Abstract: Plants are economical and sustainable factories for the production of recombinant proteins. Currently, numerous proteins produced using different plant‐based systems with applications as cosmetic and tissue culture ingredients, research and diagnostic reagents, and industrial enzymes… read more here.
Keywords: elp; elastin like; single chain; chain antibody ... See more keywords
Fabrication and Characterization of Recombinant Silk-Elastin-Like-Protein (SELP) Fiber.
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800265
Abstract: Silk-elastin-like-protein polymers (SELPs) are genetically engineered recombinant protein sequences consisting of repeating units of silk-like and elastin-like blocks. By combining these entities, it is shown that both the characteristic strength of silk and the temperature-dependent… read more here.
Keywords: silk elastin; protein; selp; elastin like ... See more keywords
Silk-elastin-like-protein/graphene-oxide Composites for Dynamic Electronic Biomaterials.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200122
Abstract: Genetically engineered silk-elastin-like-proteins (SELPs) synthesized with the combination of silk and elastin domains were bioengineered to also contain a graphene oxide binding domain. The conductivity and mechanical stability of graphene, combined with SELP-specific graphene interfaces… read more here.
Keywords: graphene; protein graphene; elastin like; silk elastin ... See more keywords
Self‐assembling systems comprising intrinsically disordered protein polymers like elastin‐like recombinamers
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Peptide Science"
DOI: 10.1002/psc.3362
Abstract: Despite lacking cooperatively folded structures under native conditions, numerous intrinsically disordered proteins (IDPs) nevertheless have great functional importance. These IDPs are hybrids containing both ordered and intrinsically disordered protein regions (IDPRs), the structure of which… read more here.
Keywords: disordered protein; like recombinamers; protein; intrinsically disordered ... See more keywords
Branched short elastin‐like peptides with temperature responsiveness obtained by EDTA‐mediated multimerization
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Peptide Science"
DOI: 10.1002/psc.3449
Abstract: Elastin‐like peptides (ELPs) exhibit a reversible phase transition, known as coacervation, triggered by temperature changes. This property makes them useful as stimuli‐responsive molecular materials for various applications. Among ELPs, short peptide chain lengths have some… read more here.
Keywords: like peptides; elastin like; temperature; multimerization ... See more keywords
Elastin-like Polymers as Nanovaccines: Protein Engineering of Self-Assembled, Epitope-Exposing Nanoparticles.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2168-4_3
Abstract: In this chapter we describe two unconventional strategies for the formulation of new nanovaccines. Both strategies are based on obtaining chimeric genes that code for proteins in which the major antigens of the pathogens are… read more here.
Keywords: nanovaccines protein; polymers nanovaccines; like polymers; protein engineering ... See more keywords
Random and oriented electrospun fibers based on a multicomponent, in situ clickable elastin-like recombinamer system for dermal tissue engineering.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.03.027
Abstract: Herein we present a system to obtain fibers from clickable elastin-like recombinamers (ELRs) that crosslink in situ during the electrospinning process itself, with no need for any further treatment to stabilize them. These ELR-click fibers… read more here.
Keywords: system; elastin like; clickable elastin; random ... See more keywords