Prevalence of relevant NS5A resistance-associated substitutions to elbasvir in genotype 1a hepatitis C virus patients in Spain
Sign Up to like & getrecommendations! Published in 2018 at "Enfermedades Infecciosas Y Microbiologia Clinica"
DOI: 10.1016/j.eimce.2017.03.028
Abstract: Abstract Resistance-associated substitutions (RASs) to the new HCV NS5A inhibitor elbasvir may limit its efficacy and lead to virological failure in HCV-GT1a-infected patients. There are no data outside clinical trials evaluating their prevalence and impact… read more here.
Keywords: elbasvir; hcv; rass; prevalence ... See more keywords
Antiviral Activity and Resistance Analysis of NS3/4A Protease Inhibitor Grazoprevir and NS5A Inhibitor Elbasvir in Hepatitis C Virus GT4 Replicons
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DOI: 10.1128/aac.00363-17
Abstract: ABSTRACT Although genotype 4 (GT4)-infected patients represent a minor overall percentage of the global hepatitis C virus (HCV)-infected population, the high prevalence of the genotype in specific geographic regions coupled with substantial sequence diversity makes… read more here.
Keywords: inhibitor; ns3 protease; elbasvir; gt4 ... See more keywords