Mechanisms of electrical remodeling in lipotoxic guinea pig heart.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.051
Abstract: OBJECTIVES To develop an adult guinea pig model of lipotoxicity and explore the underlying mechanisms associated with changes in the expression of the delayed rectifier potassium current (IK). BACKGROUND Lipotoxicity may represent a common link… read more here.
Keywords: guinea; guinea pig; lipotoxic guinea; remodeling lipotoxic ... See more keywords
Time Course of Electrical Remodeling of Native Conduction After Cardiac Resynchronization Therapy and Its Impact on Clinical Outcome.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of cardiac failure"
DOI: 10.1016/j.cardfail.2016.10.014
Abstract: BACKGROUND Cardiac resynchronization therapy (CRT) induces structural and electrical remodeling (ER) in heart failure (HF) patients. Our aim was to assess time course of ER of native conduction and mechanical remodeling after CRT and impact… read more here.
Keywords: conduction; native conduction; cardiac resynchronization; clinical outcome ... See more keywords
High Thyrotropin Is Critical for Cardiac Electrical Remodeling and Arrhythmia Vulnerability in Hypothyroidism
Sign Up to like & getrecommendations! Published in 2019 at "Thyroid"
DOI: 10.1089/thy.2018.0709
Abstract: Background: Hypothyroidism, the most common endocrine disease, induces cardiac electrical remodeling that creates a substrate for ventricular arrhythmias. Recent studies report that high thyrotropin (TSH) levels are related to cardiac electrical abnormalities and increased mortality… read more here.
Keywords: hypothyroidism; central hypothyroidism; tsh; high thyrotropin ... See more keywords
PITX2c impairment electrical remodeling increases susceptibility to atrial fibrillation
Sign Up to like & getrecommendations! Published in 2023 at "Europace"
DOI: 10.1093/europace/euad122.583
Abstract: Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): the National Research Foundation of Korea (NRF) grants funded by the Korea government (MSIT), the Korean Fund for Regenerative… read more here.
Keywords: atrial cardiomyocytes; electrical remodeling; pitx2c; pitx2 ... See more keywords
Baseline adverse electrical remodeling and the risk for ventricular arrhythmia in Cardiac Resynchronization Therapy Recipients (MADIT CRT)
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cardiovascular Electrophysiology"
DOI: 10.1111/jce.13640
Abstract: Adverse electrical remodeling (AER), represented here as the sum absolute QRST integral (SAI QRST), has previously been shown to be directly associated with the risk for ventricular arrhythmia (VA). Cardiac resynchronization therapy (CRT) is known… read more here.
Keywords: risk; risk ventricular; adverse electrical; arrhythmia cardiac ... See more keywords
PITX2 Knockout Induces Key Findings of Electrical Remodeling as Seen in Persistent Atrial Fibrillation
Sign Up to like & getrecommendations! Published in 2023 at "Circulation: Arrhythmia and Electrophysiology"
DOI: 10.1161/circep.122.011602
Abstract: Background: Electrical remodeling in human persistent atrial fibrillation is believed to result from rapid electrical activation of the atria, but underlying genetic causes may contribute. Indeed, common gene variants in an enhancer region close to… read more here.
Keywords: pitx2; isogenic control; electrical remodeling; atrial fibrillation ... See more keywords
Chronic B-Type Natriuretic Peptide Therapy Prevents Atrial Electrical Remodeling in a Rabbit Model of Atrial Fibrillation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiovascular Pharmacology and Therapeutics"
DOI: 10.1177/1074248419854749
Abstract: Background: Atrial fibrillation (AF) is an important and growing clinical problem. Current pharmacological treatments are unsatisfactory. Electrical remodeling has been identified as one of the principal pathophysiological mechanisms that promote AF, but there are no… read more here.
Keywords: atrial fibrillation; rap; bnp; atrial electrical ... See more keywords
Proarrhythmic Electrical Remodeling by Noncardiomyocytes at Interfaces With Cardiomyocytes Under Oxidative Stress
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.622613
Abstract: Life-threatening ventricular arrhythmias, typically arising from interfaces between fibrosis and surviving cardiomyocytes, are feared sequelae of structurally remodeled hearts under oxidative stress. Incomplete understanding of the proarrhythmic electrical remodeling by fibrosis limits the development of… read more here.
Keywords: proarrhythmic electrical; electrical remodeling; remodeling noncardiomyocytes; interfaces cardiomyocytes ... See more keywords
Electrical Remodeling of Left Atrium Is a Better Predictor for Recurrence Than Structural Remodeling in Atrial Fibrillation Patients Undergoing Radiofrequency Catheter Ablation.
Sign Up to like & getrecommendations! Published in 2021 at "Korean circulation journal"
DOI: 10.4070/kcj.2021.0323
Abstract: BACKGROUND AND OBJECTIVES Recurrence rates after radiofrequency catheter ablation (RFCA) in atrial fibrillation (AF) patients are not low especially in non-paroxysmal AF. The diameter of left atrium (LA) has been widely used to predict the… read more here.
Keywords: electrical remodeling; recurrence; area; radiofrequency catheter ... See more keywords