Immobilization-Free Electrochemical DNA Sensor based on signal cascade amplification strategy.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2174
Abstract: The development of convenient and efficient strategies without using complex nanomaterials or enzymes for signal amplification is very important for bioanalytical applications. Herein, a novel electrochemical DNA sensor was developed by harnessing the signal amplification… read more here.
Keywords: target dna; dna; electrochemical dna; dna sensor ... See more keywords
Facile development of highly sensitive femtomolar electrochemical DNA biosensor using gold nanoneedle-modified electrode
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Papers"
DOI: 10.1007/s11696-019-00874-y
Abstract: In this paper, a simple one-step electrochemical method was employed for the deposition of gold nanostructures. Different morphologies (Au-nanorods and Au-nanoneedles) were obtained using different concentrations of gold chloride (HAuCl 4 ·3H 2 O) solution.… read more here.
Keywords: dna biosensor; detection; dna; electrochemical dna ... See more keywords
PlcA-based nanofabricated electrochemical DNA biosensor for the detection of Listeria monocytogenes in raw milk samples
Sign Up to like & getrecommendations! Published in 2020 at "3 Biotech"
DOI: 10.1007/s13205-020-02315-0
Abstract: The electrochemical DNA biosensor has been developed for the detection of Listeria monocytogenes in raw milk samples. The electrochemical studies of the developed biosensor was recorded by cyclic voltammetry (CV) and electrochemical impedance (EI) using… read more here.
Keywords: dna biosensor; detection; detection listeria; electrochemical dna ... See more keywords
Signal enhancement of electrochemical DNA biosensors for the detection of trace heavy metals
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Electrochemistry"
DOI: 10.1016/j.coelec.2019.04.007
Abstract: Abstract Heavy-metal pollution has attracted intensive attention from the public because of the severe threats of heavy metals to the ecosystem and human health. Ultralow concentration of heavy metals in aquatic environment leads to the urgent… read more here.
Keywords: dna biosensors; heavy metals; heavy metal; electrochemical dna ... See more keywords
A novel single-pot synthesis of dinuclear and mononuclear copper(II) complexes with sterically demanding Schiff bases: Structural, spectral, magnetic, electrochemical, DNA binding and theoretical investigation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.129955
Abstract: Abstract Two dinuclear CuII complexes, cyclo-[Cu2(LtBu)Cl2]•4EtOH] (monoclinic P21/n) (2) and cyclo-[Cu2(LMe)1.5Cl•0.5H2O]Cl•(H2O) (hexagonal P6) (3) (where cyclo-H2LtBu = cyclo-bis{2-[benz(N-ethan-1,2-diyl)imidoyl][6-benzimidoyl][4-tert-butyl]phenol}, and cyclo-H2LMe = cyclo-bis{2-[benz(N-propan-1,3-diyl)imidoyl][6-benzimidoyl][4-methylphenol}, and two mononuclear CuII complexes, [Cu(LtBu)(OH2)] (monoclinic P21/c) (4) and [Cu(mdbp)2] (monoclinic P21/c) (5) (where… read more here.
Keywords: schiff; copper; electrochemical dna; cyclo ... See more keywords
The strategies of DNA immobilization and hybridization detection mechanism in the construction of electrochemical DNA sensor: A review
Sign Up to like & getrecommendations! Published in 2017 at "Sensing and bio-sensing research"
DOI: 10.1016/j.sbsr.2017.09.001
Abstract: Abstract In recent years, electrochemical deoxyribonucleic acid (DNA) sensor has recently emerged as promising alternative clinical diagnostic devices especially for infectious disease by exploiting DNA recognition events and converting them into an electrochemical signal. This… read more here.
Keywords: detection; immobilization; dna; electrochemical dna ... See more keywords
A ratiometric electrochemical DNA biosensor for detection of exosomal MicroRNA.
Sign Up to like & getrecommendations! Published in 2020 at "Talanta"
DOI: 10.1016/j.talanta.2019.120298
Abstract: The detection of exosomal microRNAs (miRNAs) derived from cancer cells with sensitive and selective methods has stimulated increasing interest due to its potential utility in the application of tumor diagnosis. Here, we developed a ratiometric… read more here.
Keywords: dna biosensor; detection; electrochemical dna; biosensor ... See more keywords
Development of a Single-Molecule Nanobalance Ratiometric Electrochemical DNA Biosensor Using a Triblock Poly-Adenine Probe.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05750
Abstract: The development of electrochemical DNA biosensors has been limited by their reliability and reproducibility due to many interfering factors such as electrode properties, DNA surface densities, and complex biological samples. In this work, we developed… read more here.
Keywords: single molecule; electrochemical dna; development; polya ... See more keywords
Multiplex Real-Time Loop-Mediated Isothermal Amplification Using an Electrochemical DNA Chip Consisting of a Single Liquid-Flow Channel.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b05284
Abstract: We developed a multiplex system capable of simultaneously quantifying different target sequences by applying an electrochemical DNA chip that consists of single liquid-flow channel with primers designed for loop-mediated isothermal amplification (LAMP). We applied this… read more here.
Keywords: dna chip; electrochemical dna; flow channel; dna ... See more keywords
Detecting Attomolar DNA-Damaging Anticancer Drug Activity in Cell Lysates with Electrochemical DNA Devices.
Sign Up to like & getrecommendations! Published in 2021 at "ACS sensors"
DOI: 10.1021/acssensors.1c00365
Abstract: Here, we utilize electrochemical DNA devices to quantify and understand the cancer-specific DNA-damaging activity of an emerging drug in cellular lysates at femtomolar and attomolar concentrations. Isobutyl-deoxynyboquinone (IB-DNQ), a potent and tumor-selective NAD(P)H quinone oxidoreductase… read more here.
Keywords: dna devices; dna damaging; dna; electrochemical dna ... See more keywords
Ultrasensitive pathogen detection with a rolling circle amplification-empowered multiplex electrochemical DNA sensor.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc05181d
Abstract: We report a highly sensitive and selective multiplex assay by empowering an electrochemical DNA sensor with isothermal rolling circle amplification. The assay could simultaneously detect and discriminate three common entero-pathogens in a single reaction, with… read more here.
Keywords: electrochemical dna; dna sensor; rolling circle; circle amplification ... See more keywords