Electrochemical, Iodine-Mediated α-CH Amination of Ketones by Umpolung of Silyl Enol Ethers.
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DOI: 10.1021/acs.orglett.0c02068
Abstract: The electrochemical, oxidative Umpolung reaction of silyl enol ethers utilizing simple iodide salts for the synthesis of α-amino ketones is described. The products were isolated in excellent yields of up to 100%, and various functionalized… read more here.
Keywords: silyl enol; electrochemical iodine; enol ethers; mediated amination ... See more keywords