Development of transient trapping micellar electrokinetic chromatography coupled with mass spectrometry for steroids analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Chirality"
DOI: 10.1002/chir.23489
Abstract: An on-line sample preconcentration technique based on transient trapping (tr-trapping) in micellar electrokinetic chromatography (MEKC) was applied for steroid detection with UV (tr-trapping-UV) and electrospray ionization mass spectrometry detection (tr-trapping-ESI-MS). ESI-MS was used to improve… read more here.
Keywords: trapping micellar; electrokinetic chromatography; detection; micellar electrokinetic ... See more keywords
Derivatizing assay for the determination of aldehydes using micellar electrokinetic chromatography
Sign Up to like & getrecommendations! Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201600483
Abstract: In this work, the use of a novel derivatization agent for the determination of aldehydes (in this particular case: formaldehyde, acetaldehyde, propionaldehyde, and valeraldehyde) using micellar electrokinetic chromatography is reported. The derivatization reaction is based… read more here.
Keywords: micellar electrokinetic; determination aldehydes; using micellar; electrokinetic chromatography ... See more keywords
Determination of lipid bilayer affinities and solvation characteristics by electrokinetic chromatography using polymer‐bound lipid bilayer nanodiscs
Sign Up to like & getrecommendations! Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700308
Abstract: Styrene‐maleic acid polymer‐bound lipid bilayer nanodiscs have been investigated and characterized by electrokinetic chromatography. Linear solvation energy relationship analysis was employed to characterize the changes in solvation environment of nanodiscs of varied belt to lipid… read more here.
Keywords: electrokinetic chromatography; chemistry; lipid bilayer; composition ... See more keywords
A novel reverse migration micellar electrokinetic chromatography method for in‐capillary screening and quantifying of antioxidant components in Sanyetangzhiqing using 2,2′‐Azinobis‐(3‐ethylbenzthiazoline‐6‐sulphonate) as oxidation‐free radical
Sign Up to like & getrecommendations! Published in 2022 at "ELECTROPHORESIS"
DOI: 10.1002/elps.202100330
Abstract: A novel method of reverse migration micellar electrokinetic chromatography (RM‐MEKC) using 2,2′‐azinobis‐(3‐ethylbenzthiazoline‐6‐sulphonate) as oxidation‐free radical was developed to screen the major antioxidants from Sanyetangzhiqing (SYTZQ), which is a new patent drug for diabetes. For simultaneous… read more here.
Keywords: using azinobis; electrokinetic chromatography; reverse migration; micellar electrokinetic ... See more keywords
Sphingomyelin ability to act as chiral selector using nanodisc electrokinetic chromatography.
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2018.05.002
Abstract: Understanding how stereochemistry affects interactions with cell membranes is important for effective drug development. Chirality has been shown to greatly effect pharmaceutical distribution and metabolism within the cell. However it has been thought that interactions… read more here.
Keywords: electrokinetic chromatography; nanodisc electrokinetic; chemistry; sphingomyelin ability ... See more keywords
Biopartitioning micellar electrokinetic chromatography – Concept study of cationic analytes
Sign Up to like & getrecommendations! Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.104518
Abstract: Abstract In the early stages of drug discovery, beyond the biological activity screening, the physicochemical properties including lipophilicity, ionization, solubility as well as metabolic profiling and protein-binding affinity should be determined for each drug candidate.… read more here.
Keywords: chromatography; electrokinetic chromatography; chromatography concept; concept study ... See more keywords
Use of single and dual systems of γ-cyclodextrin or γ -cyclodextrin/L-Carnitine derived ionic liquid for the enantiomeric determination of cysteine by electrokinetic chromatography. A comparative study
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106596
Abstract: Abstract Two electrokinetic chromatography methods based on the use of γ-CD as the sole chiral selector or the combination of γ-CD and L-Carnitine methyl ester bis(trifluoromethane)sulfonimide were developed and validated in this work for the… read more here.
Keywords: electrokinetic chromatography; cysteine; use; determination cysteine ... See more keywords
Determination of Saikosaponins in Bupleuri Radix by Micellar Electrokinetic Chromatography with Experimental Design
Sign Up to like & getrecommendations! Published in 2018 at "Analytical Letters"
DOI: 10.1080/00032719.2017.1392548
Abstract: ABSTRACT The important pharmacological components of Bupleuri radix include saikosaponins a–d. A multivariable approach with experimental design was employed in this study to determine four saikosaponins in different species of Bupleuri radix by cyclodextrin-modified micellar… read more here.
Keywords: bupleuri radix; experimental design; electrokinetic chromatography; micellar electrokinetic ... See more keywords
Chiral Capillary Electrokinetic Chromatography: Principle and Applications, Detection and Identification, Design of Experiment, and Exploration of Chiral Recognition Using Molecular Modeling
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26102841
Abstract: This work reviews the literature of chiral capillary electrokinetic chromatography from January 2016 to March 2021. This is done to explore the state-of-the-art approach and recent developments carried out in this field. The separation principle… read more here.
Keywords: molecular modeling; electrokinetic chromatography; capillary electrokinetic; chiral recognition ... See more keywords
Comparison of the Performance of Different Bile Salts in Enantioselective Separation of Palonosetron Stereoisomers by Micellar Electrokinetic Chromatography
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27165233
Abstract: Bile salts are a category of natural chiral surfactants which have ever been used as the surfactant and chiral selector for the separation of many chiral compounds by micellar electrokinetic chromatography (MEKC). In our previous… read more here.
Keywords: different bile; electrokinetic chromatography; micellar electrokinetic; separation ... See more keywords