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Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1693-2_9
Abstract: Modeling human cardiac tissues in vitro is essential to elucidate the biological mechanisms related to the heart physiopathology, possibly paving the way for new treatments. Organs-on-chips have emerged as innovative tools able to recreate tissue-specific…
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Keywords:
heart chip;
heart;
chip model;
electromechanical stimulation ... See more keywords
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Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10175-3
Abstract: Adult cardiac tissue undergoes a rapid process of dedifferentiation when cultured outside the body. The in vivo environment, particularly constant electromechanical stimulation, is fundamental to the regulation of cardiac structure and function. We investigated the…
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Keywords:
electromechanical stimulation;
adult;
adult cardiac;
cardiac tissue ... See more keywords