An uncharacteristically low-potential flavin governs the energy landscape of electron bifurcation
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2117882119
Abstract: Significance Nature has long been an inspiration for materials design, as it exemplifies exquisite control of both matter and energy. Electron bifurcation, a mechanism employed in biological systems to drive thermodynamically unfavorable and energetically challenging… read more here.
Keywords: energy landscape; energy; electron bifurcation; electron ... See more keywords
Three-megadalton complex of methanogenic electron-bifurcating and CO2-fixing enzymes
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.abg5550
Abstract: Description Methanogenesis megacomplex An important first step in methanogenesis is the conversion of carbon dioxide to a reduced one-carbon formyl unit that is a substrate for downstream steps. This reaction is catalyzed by a complex… read more here.
Keywords: three megadalton; co2; electron bifurcation; reaction ... See more keywords
On the Natural History of Flavin-Based Electron Bifurcation
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.01357
Abstract: Electron bifurcation is here described as a special case of the continuum of electron transfer reactions accessible to two-electron redox compounds with redox cooperativity. We argue that electron bifurcation is foremost an electrochemical phenomenon based… read more here.
Keywords: electron bifurcation; electron; redox; flavin based ... See more keywords
Site-Differentiated Iron–Sulfur Cluster Ligation Affects Flavin-Based Electron Bifurcation Activity
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12090823
Abstract: Electron bifurcation is an elegant mechanism of biological energy conversion that effectively couples three different physiologically relevant substrates. As such, enzymes that perform this function often play critical roles in modulating cellular redox metabolism. One… read more here.
Keywords: site; electron bifurcation; iron sulfur; site differentiated ... See more keywords