Radicals as Exceptional Electron-Withdrawing Groups: Nucleophilic Aromatic Substitution of Halophenols Via Homolysis-Enabled Electronic Activation.
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DOI: 10.1021/jacs.2c10296
Abstract: While heteroatom-centered radicals are understood to be highly electrophilic, their ability to serve as transient electron-withdrawing groups and facilitate polar reactions at distal sites has not been extensively developed. Here, we report a new strategy… read more here.
Keywords: electron withdrawing; homolysis; electronic activation; substitution ... See more keywords