Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
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DOI: 10.1038/nchembio.2494
Abstract: O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is an essential human glycosyltransferase that adds O-GlcNAc modifications on numerous proteins. However, little is known about how OGT recognizes various protein substrates. Here we report GlcNAc electrophilic probes (GEPs)… read more here.
Keywords: recognition; electrophilic probes; substrate recognition; glcnac transferase ... See more keywords