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Published in 2022 at "Biotechnology Journal"
DOI: 10.1002/biot.202100325
Abstract: The increased use of biopharmaceuticals calls for improved means of bioprocess monitoring. In this work, capillary electrophoresis (CE) and microchip electrophoresis (MCE) methods were developed and applied for the analysis of amino acids (AAs) in…
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Keywords:
microchip electrophoresis;
cultivation;
analysis;
amino ... See more keywords
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Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201800608
Abstract: We report a fluorescent probe that is highly sensitive and selective for serum albumins. Signal transduction results from the disassembly of fluorescence‐quenched aggregates upon binding to human serum albumin (HSA). The probe offers a rapid…
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Keywords:
fluorophore aggregates;
electrophoresis;
selective detection;
electrophoresis gels ... See more keywords
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Published in 2020 at "Chirality"
DOI: 10.1002/chir.23268
Abstract: Abstract Besides the abuse of well‐known illicit drugs, consumers discovered new synthetic compounds with similar effects but minor alterations in their chemical structure. Originally, these so‐called novel psychoactive substances (NPS) have been created to circumvent…
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Keywords:
cyclodextrin;
determination chiral;
electrophoresis;
chiral status ... See more keywords
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Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201600331
Abstract: One of the most cited limitations of capillary (and microchip) electrophoresis is the poor sensitivity. This review continues to update this series of biennial reviews, first published in Electrophoresis in 2007, on developments in the…
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Keywords:
advances enhancing;
line;
capillaries microchips;
electrophoresis ... See more keywords
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Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201600519
Abstract: Capillary and microfluidic chip electrophoresis technologies are heavily utilized for development, characterization, release, and stability testing of biopharmaceuticals. Within the biopharmaceutical industry, CE‐SDS and M‐CGE are commonly used for purity determination by separation and quantitation…
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Keywords:
platform method;
method;
electrophoresis;
stability ... See more keywords
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Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700016
Abstract: The racemic N‐methyl‐d‐aspartate receptor antagonist ketamine is used in anesthesia, analgesia and the treatment of depressive disorders. It is known that interactions of hydroxylated norketamine metabolites and 5,6‐dehydronorketamine (DHNK) with the α7‐nicotinic acetylcholine receptor and…
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Keywords:
capillary electrophoresis;
ketamine;
cyclodextrin highly;
electrophoresis ... See more keywords
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Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700097
Abstract: Nanomaterials are in analytical science used for a broad range of purposes, covering the area of sample pretreatment as well as separation, detection, and identification of target molecules. This part of the review covers capillary…
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Keywords:
capillary electrophoresis;
part capillary;
electrophoresis;
electrophoresis nanomaterials ... See more keywords
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Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700178
Abstract: Nanomaterials have found an important place in Analytical Chemistry and, in particular, in Separation Science. Among them, metal‐organic frameworks, magnetic and non‐magnetic nanoparticles, carbon nanotubes and graphene, as well as their combinations, are the most…
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Keywords:
capillary electrophoresis;
recent applications;
applications nanomaterials;
electrophoresis ... See more keywords
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Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700187
Abstract: Antimicrobial peptides (AMPs) are usually small and cationic biomolecules with broad‐spectrum antimicrobial activities against pathogens. Purifying them from complex samples is essential to study their physiochemical properties. In this work, free‐flow zone electrophoresis (FFZE) was…
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Keywords:
electrophoresis;
filtration chromatography;
free flow;
gel filtration ... See more keywords
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Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700217
Abstract: In this paper, we describe development of a high‐throughput, highly sensitive method based on Lab Chip CGE‐SDS platform for purity determination and characterization of virus‐like particle (VLP) vaccines. A capillary gel electrophoresis approach requiring about…
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Keywords:
method;
electrophoresis;
purity;
platform ... See more keywords
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Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700307
Abstract: The use of an electric field in free‐flow zone electrophoresis (FFZE) automatically leads to Joule heating yielding a higher temperature at the center of the separation chamber relative to that around the channel walls. For…
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Keywords:
zone;
temperature;
stream;
joule heating ... See more keywords