Quantifying protein aggregation kinetics using electrospray differential mobility analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.112845
Abstract: Protein aggregation is a critical concern in bioprocessing, where its presence can result in serious adverse interactions in clinical end-use applications. In this study, an aerosol-based technique, electrospray differential mobility analysis (ES-DMA), was used to… read more here.
Keywords: aggregation; mobility analysis; differential mobility; electrospray differential ... See more keywords
Nano electrospray differential mobility analysis based size-selection of liposomes and very-low density lipoprotein particles for offline hyphenation to MALDI mass spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.112998
Abstract: Gas-phase electrophoresis of single-charged analytes (nanoparticles) enables their separation according to the surface-dry particle size (Electrophoretic Mobility Diameter, EMD), which corresponds to the diameter of spherical shaped particles. Employing a nano Electrospray Differential Mobility Analyzer… read more here.
Keywords: mobility; electrospray differential; nano electrospray; differential mobility ... See more keywords
Absolute Quantification of Bionanoparticles by Electrospray Differential Mobility Analysis: An Application to Lipoprotein Particle Concentration Measurements.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.6b02909
Abstract: This study presents an upgraded electrospray differential mobility analysis (ES-DMA) setup for the absolute quantification of bionanoparticle concentrations in biological samples, with a special focus on non-high-density-lipoprotein particle concentrations (non-HDL-P). Metrological characterization of the system's… read more here.
Keywords: mobility analysis; differential mobility; electrospray differential; particle ... See more keywords