Desorption Electrospray Ionization Mass Spectrometry Assay for Label‐Free Characterization of SULT2B1b Enzyme Kinetics
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200043
Abstract: The sulfotransferase (SULT) 2B1b, which catalyzes the sulfonation of 3β‐hydroxysteroids, has been identified as a potential target for prostate cancer treatment. However, a major limitation for SULT2B1b‐targeted drug discovery is the lack of robust assays… read more here.
Keywords: label free; sult2b1b; mass spectrometry; desorption electrospray ... See more keywords
High‐Throughput Drug Derivatization and Bioassay by Desorption Electrospray Ionization Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2025 at "Chempluschem"
DOI: 10.1002/cplu.202500164
Abstract: Adapting high‐throughput (HT) synthetic methods to the modification of drugs and to testing of their bioactivity should expedite drug discovery. Herein, the applicability of HT desorption electrospray ionization mass spectrometry (DESI MS) to achieve late‐stage… read more here.
Keywords: desorption electrospray; high throughput; mass spectrometry; ionization mass ... See more keywords
Coupling of capillary electrophoresis with electrospray ionization multiplexing ion mobility spectrometry
Sign Up to like & getrecommendations! Published in 2019 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201800462
Abstract: In this work, ion mobility spectrometry (IMS) function as a detector and another dimension of separation was coupled with CE to achieve two‐dimensional separation. To improve the performance of hyphenated CE‐IMS instrument, electrospray ionization correlation… read more here.
Keywords: electrophoresis; ion mobility; mobility spectrometry; ion ... See more keywords
High-throughput screening of toxic substances by extractive electrospray ionization mass spectrometry and their identification via databank construction
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1520-x
Abstract: AbstractMore than 200 toxic substances (including narcotic drugs, psychotropic drugs, organic phosphorus compounds, carbamates, pyrethroids and other pesticides, veterinary drugs, rodenticides, natural toxins, and other drugs) were identified and quantified using an ion-trap mass spectrometer.… read more here.
Keywords: methodology; mass spectrometry; extractive electrospray; mass ... See more keywords
Observation of charged droplets from electrospray ionization (ESI) plumes in API mass spectrometers
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-021-03452-y
Abstract: Electrospray ionization (ESI) generates bare analyte ions from charged droplets, which result from spraying a liquid in a strong electric field. Experimental observations available in the literature suggest that at least a significant fraction of… read more here.
Keywords: charged droplets; ionization esi; mass; electrospray ionization ... See more keywords
Understanding the electrospray ionization response factors of per- and poly-fluoroalkyl substances (PFAS)
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-021-03545-8
Abstract: Per- and polyfluoroalkyl substances (PFAS) are used extensively in commercial products. Their unusual solubility properties make them an ideal class of compounds for various applications. However, these same properties have led to significant contamination and… read more here.
Keywords: response factors; electrospray ionization; substances pfas; understanding electrospray ... See more keywords
Tannic Acid: a Novel Calibrator for Facile and Accurate Mass Measurement of Electrospray Ionization Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2019 at "Journal of The American Society for Mass Spectrometry"
DOI: 10.1007/s13361-019-02211-9
Abstract: AbstractAccurate mass calibration is beneficial to the identification of the unknown compounds quickly and accurately. The ESI mass spectrum of tannic acid (TA) tends to a normal distribution of the cluster ion peaks in m/z… read more here.
Keywords: tannic acid; mass spectrometry; novel calibrator; mass ... See more keywords
Sodium dodecyl sulfate removal during electrospray ionization using cyclodextrins as simple sample solution additive for improved mass spectrometric detection of peptides.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2017.12.012
Abstract: Sodium dodecyl sulfate (SDS) removal is a vital procedure in SDS-assisted bottom-up proteomics because SDS affects the quality of the data in electrospray ionization mass spectrometry (ESI-MS). SDS removal methods provide efficient removal of SDS… read more here.
Keywords: dodecyl sulfate; removal; sodium dodecyl; sds ... See more keywords
Rapid screening of basic colorants in processed vegetables through mass spectrometry using an interchangeable thermal desorption electrospray ionization source.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.01.003
Abstract: Thermal desorption electrospray ionization/mass spectrometry (TD-ESI-MS) employing a quickly interchangeable ionization source is a relatively new ambient ionization mass spectrometric technique that has had, to date, only a limited number of applications related to food… read more here.
Keywords: thermal desorption; desorption electrospray; source; ionization source ... See more keywords
Profiling and quantification of lipids in cold-pressed rapeseed oils based on direct infusion electrospray ionization tandem mass spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.01.146
Abstract: Microwave pretreatment of rapeseeds prior to cold-pressing is a simple and desirable method for producing high quality oils. In this study, a rapid and sensitive lipid profiling platform employing an accurate quantification strategy was established… read more here.
Keywords: ionization tandem; infusion electrospray; based direct; microwave pretreatment ... See more keywords
Influence of iron redox abilities on the electrospray ionization collision induced dissociation of iron complexes with methoxylated flavonoids
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Mass Spectrometry"
DOI: 10.1016/j.ijms.2019.116216
Abstract: Abstract By using electrospray ionization mass spectrometry two types of iron complexes of methoxylated flavonoids were generated. Depending on the flavonoid structure, the complexes corresponded to the ions [(M-H)2+Fe]+ or [M2+FeCl]+, M stands for the… read more here.
Keywords: complexes methoxylated; iron; collision induced; electrospray ionization ... See more keywords