Electrostatically Mediated Protein-Protein Interactions for Monoclonal Antibodies: A Combined Experimental and Coarse-Grained Molecular Modeling Approach.
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DOI: 10.1016/j.xphs.2018.11.004
Abstract: Electrostatically mediated protein-protein interactions (PPI) can influence key product properties such as solubility, solution viscosity, and aggregation rates. Predictive models would allow for candidates/formulations to be screened with little or no protein material. Three monoclonal… read more here.
Keywords: protein interactions; monoclonal antibodies; electrostatically mediated; protein protein ... See more keywords