Analysis of the C. elegans Germline Stem Cell Pool.
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DOI: 10.1007/978-1-4939-4017-2_1
Abstract: The Caenorhabditis elegans germline is an excellent model for studying the regulation of a pool of stem cells and progression of cells from a stem cell state to a differentiated state. At the tissue level,… read more here.
Keywords: analysis; pool; stem cell; cell ... See more keywords
CCM-3 Promotes C. elegans Germline Development by Regulating Vesicle Trafficking Cytokinesis and Polarity
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DOI: 10.1016/j.cub.2017.02.028
Abstract: Cerebral cavernous malformations (CCMs) are vascular defects of the CNS that arise from loss of integrity of the endothelial cells lining blood capillaries, causing leakage of blood into the brain [1]. This results in headaches,… read more here.
Keywords: cytokinesis; ccm; polarity; localization ... See more keywords
Reevaluation of the role of LIP-1 as an ERK/MPK-1 dual specificity phosphatase in the C. elegans germline
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DOI: 10.1073/pnas.2113649119
Abstract: Significance The RAS–ERK pathway is critical for metazoan development. In development, ERK activity is regulated by a balance of phosphorylation of ERK by MEK (MAPK kinase) and dephosphorylation by DUSPs (dual specificity phosphatases). LIP-1, a… read more here.
Keywords: mpk; function; dual specificity; elegans germline ... See more keywords
Developmental dynamics of gene expression and alternative polyadenylation in the Caenorhabditis elegans germline
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DOI: 10.1186/s13059-017-1369-x
Abstract: BackgroundThe 3′ untranslated regions (UTRs) of mRNAs play a major role in post-transcriptional regulation of gene expression. Selection of transcript cleavage and polyadenylation sites is a dynamic process that produces multiple transcript isoforms for the… read more here.
Keywords: gene expression; caenorhabditis elegans; polyadenylation; expression ... See more keywords