MicroRNA‐320a inhibits invasion and metastasis in osteosarcoma by targeting cytoplasmic polyadenylation element‐binding protein 1
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.2919
Abstract: Osteosarcoma is a primary malignant bone tumor, which affects children, adolescents, and young adults commonly. MicroRNAs (miRNAs) have been proved to be dysregulated in different cancers, including osteosarcoma. Although miR‐320a has been implicated in many… read more here.
Keywords: cytoplasmic polyadenylation; polyadenylation element; osteosarcoma; binding protein ... See more keywords
Rapid antidepressant‐like effect of Fructus Aurantii depends on cAMP‐response element binding protein/Brain‐derived neurotrophic facto by mediating synaptic transmission
Sign Up to like & getrecommendations! Published in 2020 at "Phytotherapy Research"
DOI: 10.1002/ptr.6812
Abstract: Several studies reported the relative antidepressant effects of Fructus Aurantii (FRA) with repeated treatment, the rapid antidepressant effects of FRA and the underlying mechanisms remained unclear. We, therefore, examined the rapid antidepressant actions of FRA… read more here.
Keywords: camp response; fructus aurantii; element binding; rapid antidepressant ... See more keywords
Regulatory roles of sterol regulatory element-binding protein (SREBP) on lipid metabolism in marine invertebrate Chlamys nobilis.
Sign Up to like & getrecommendations! Published in 2018 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2018.03.023
Abstract: Abstract Sterol regulatory element-binding protein (SREBP) has mainly been studied in vertebrates in which lipogenesis is regulated in both liver and adipose tissue. There is, however, a paucity of information on bivalves, in which lipogenesis… read more here.
Keywords: regulatory element; srebp; protein srebp; binding protein ... See more keywords
Extracellular Acidic pH Activates the Sterol Regulatory Element-Binding Protein 2 to Promote Tumor Progression.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.02.006
Abstract: Conditions of the tumor microenvironment, such as hypoxia and nutrient starvation, play critical roles in cancer progression. However, the role of acidic extracellular pH in cancer progression is not studied as extensively as that of hypoxia.… read more here.
Keywords: regulatory element; element binding; sterol regulatory; cancer ... See more keywords
Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09152-7
Abstract: Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regulate lipid biosynthesis and adipogenesis by controlling the expression of several enzymes required for cholesterol, fatty acid, triacylglycerol and phospholipid synthesis. In… read more here.
Keywords: metabolism; regulatory element; mechanical cues; sterol regulatory ... See more keywords
Dehydration responsive element binding transcription factors and their applications for the engineering of stress tolerance
Sign Up to like & getrecommendations! Published in 2017 at "Journal Of Experimental Botany"
DOI: 10.1093/jxb/erx118
Abstract: Dehydration responsive element binding (DREB) factors or CRT element binding factors (CBFs) are members of the AP2/ERF family, which comprises a large number of stress-responsive regulatory genes. This review traverses almost two decades of research,… read more here.
Keywords: responsive element; stress; stress tolerance; element binding ... See more keywords
PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein
Sign Up to like & getrecommendations! Published in 2018 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noy068
Abstract: Background Hyperactivation of phosphoinositide 3-kinase (PI3K) signaling is common in cancers, but the precise role of the pathway in glioma biology remains to be determined. Some understanding of PI3K signaling mechanisms in brain cancer comes… read more here.
Keywords: camp response; pi3k; binding protein; element binding ... See more keywords
Evolution of the DEHYDRATION-RESPONSIVE ELEMENT BINDING PROTEIN subfamily in green plants.
Sign Up to like & getrecommendations! Published in 2022 at "Plant physiology"
DOI: 10.1093/plphys/kiac286
Abstract: Adapting to unfavorable environments is a necessary step in plant terrestrialization and radiation. The dehydration-responsive element binding protein (DREB) subfamily plays a pivotal role in plant abiotic stress regulation. However, relationships between the origin and… read more here.
Keywords: binding protein; element binding; responsive element; dreb subfamily ... See more keywords
Sterol regulatory element binding protein‐1 (SREBP1) gene expression is similarly increased in polycystic ovary syndrome and endometrial cancer
Sign Up to like & getrecommendations! Published in 2017 at "Acta Obstetricia et Gynecologica Scandinavica"
DOI: 10.1111/aogs.13106
Abstract: Women with polycystic ovary syndrome have a three‐fold higher risk of endometrial cancer. Insulin resistance and hyperlipidemia may be pertinent factors in the pathogenesis of both conditions. The aim of this study was to investigate… read more here.
Keywords: polycystic ovary; regulatory element; endometrial cancer; ovary syndrome ... See more keywords
Knockdown of Anopheles dirus far upstream element-binding protein gene lower oocyst numbers of Plasmodium vivax.
Sign Up to like & getrecommendations! Published in 2023 at "Medical and veterinary entomology"
DOI: 10.1111/mve.12662
Abstract: The modulation of gene expression levels of Anopheles dirus on Plasmodium vivax infection at the ookinete and oocyst stages was previously reported. In the present study, several upregulated An. dirus genes were selected based on… read more here.
Keywords: binding protein; element binding; oocyst; far upstream ... See more keywords
cAMP Response Element-Binding Protein- and Phosphorylation-Dependent Regulation of Tyrosine Hydroxylase by PAK4: Implications for Dopamine Replacement Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Molecules and Cells"
DOI: 10.14348/molcells.2021.2250
Abstract: Parkinson’s disease (PD) is characterized by a progressive loss of dopamine-producing neurons in the midbrain, which results in decreased dopamine levels accompanied by movement symptoms. Oral administration of l-3,4-dihydroxyphenylalanine (L-dopa), the precursor of dopamine, provides… read more here.
Keywords: camp response; binding protein; element binding; tyrosine hydroxylase ... See more keywords