Targeting elevated heme levels to treat a mouse model for Diamond-Blackfan Anemia.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental hematology"
DOI: 10.1016/j.exphem.2021.10.005
Abstract: Diamond-Blackfan anemia (DBA) is a rare genetic disorder in which patients present a scarcity of erythroid precursors in an otherwise normocellular bone marrow. Most, but not all, patients carry mutations in ribosomal proteins such as… read more here.
Keywords: elevated heme; heme levels; heme; rps19 deficient ... See more keywords
Elevated heme impairs macrophage phagocytosis in endometriosis.
Sign Up to like & getrecommendations! Published in 2019 at "Reproduction"
DOI: 10.1530/rep-19-0028
Abstract: Endometriosis (EMS) is a chronic inflammatory disease characterized by the presence of extrauterine endometrial tissues. It has been previously reported that the refluxed blood containing viable endometrial tissues and the defective elimination of peritoneal macrophages… read more here.
Keywords: macrophage; endometriosis; macrophage phagocytosis; elevated heme ... See more keywords