Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0182472
Abstract: Background DNA methylation is affected by the activities of the key enzymes and intermediate metabolites of the one-carbon pathway, one of which involves homocysteine. We investigated the effect of the well-known genetic variant associated with… read more here.
Keywords: methylation; homocysteine; elevated homocysteine; mthfr 677c ... See more keywords
Elevated homocysteine levels, white matter abnormalities and cognitive impairment in patients with late-life depression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.931560
Abstract: Background Cognitive impairment in late−life depression (LLD) is considered to be caused by neurodegenerative changes. Elevated homocysteine (Hcy) levels may be linked to cognitive abnormalities associated with LLD. The important role of white matter (WM)… read more here.
Keywords: patients lld; hcy levels; late life; elevated homocysteine ... See more keywords
Associations of Serum and Red Blood Cell Folate With All-Cause and Cardiovascular Mortality Among Hypertensive Patients With Elevated Homocysteine
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.849561
Abstract: Objectives This study aims to explore the associations between serum and red blood cell (RBC) folate as indicators of short- and long-term folate status, respectively, and all-cause as well as CVD mortality among hypertensive patients… read more here.
Keywords: mortality among; elevated homocysteine; patients elevated; hypertensive patients ... See more keywords