Ascertainment Bias in the Association Between Elevated Lipoprotein(a) and Familial Hypercholesterolemia.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2020.03.065
Abstract: BACKGROUND Lipoprotein(a) is an atherogenic low-density lipoprotein-like particle and circulating levels are largely determined by genetics. Patients with familial hypercholesterolemia (FH) have elevated lipoprotein(a); however, it remains unclear why. OBJECTIVES This study compared the levels… read more here.
Keywords: association; elevated lipoprotein; familial hypercholesterolemia; ascertainment ... See more keywords
Elevated lipoprotein A in acute on chronic CTEPH with cardiogenic shock: a case report
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Community Hospital Internal Medicine Perspectives"
DOI: 10.1080/20009666.2021.1955450
Abstract: ABSTRACT The natural history of most thrombi undergoes total or near total resolution, but the thrombi in chronic thromboembolic pulmonary hypertension (CTEPH) do not resolve completely and subsequently increase the pulmonary vascular resistance. We hypothesised… read more here.
Keywords: cteph cardiogenic; chronic cteph; elevated lipoprotein; lipoprotein acute ... See more keywords
Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a)
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehaa171
Abstract: Abstract Aims Elevated lipoprotein(a) [Lp(a)] is strongly associated with an increased cardiovascular disease (CVD) risk. We previously reported that pro-inflammatory activation of circulating monocytes is a potential mechanism by which Lp(a) mediates CVD. Since potent… read more here.
Keywords: inflammatory activation; patients elevated; treatment; circulating monocytes ... See more keywords
Familial Hypercholesterolemia and Elevated Lipoprotein(a): Cascade Testing and Other Implications for Contextual Models of Care
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.905941
Abstract: Elevated lipoprotein(a) [Lp(a)], a predominantly genetic disorder, is a causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valvular disease, particularly in patients with familial hypercholesterolemia (FH), a Tier I genomic condition. The… read more here.
Keywords: models care; elevated lipoprotein; risk; cascade testing ... See more keywords