IL-27 is elevated in sepsis with acute hepatic injury and promotes hepatic damage and inflammation in the CLP model.
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DOI: 10.1016/j.cyto.2019.154936
Abstract: BACKGROUND Immuno-inflammation plays an important role in the pathophysiological process of sepsis-associated acute hepatic injury (AHI). Interleukin 27 (IL-27) is an important inflammatory regulator; however, its role in this condition is not clear. METHODS The… read more here.
Keywords: acute hepatic; serum; elevated sepsis; injury ... See more keywords