Elexacaftor is a CFTR potentiator and acts synergistically with ivacaftor during acute and chronic treatment
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DOI: 10.1038/s41598-021-99184-1
Abstract: Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), which lead to early death due to progressive lung disease. The development of small-molecule modulators that directly interact with CFTR… read more here.
Keywords: cftr potentiator; elexacaftor cftr; elexacaftor; acute chronic ... See more keywords