Serum alpha-mannosidase as an additional barrier to eliciting oligomannose-specific HIV-1-neutralizing antibodies
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DOI: 10.1038/s41598-020-64500-8
Abstract: Oligomannose-type glycans on HIV-1 gp120 form a patch that is targeted by several broadly neutralizing antibodies (bnAbs) and that therefore is of interest to vaccine design. However, attempts to elicit similar oligomannose-specific bnAbs by immunizing… read more here.
Keywords: eliciting oligomannose; oligomannose specific; mannosidase trimming; mannosidase ... See more keywords