Intratumoral cancer chemotherapy with a carrier-based immunogenic cell death eliciting platinum (IV) agent.
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DOI: 10.1021/acs.molpharmaceut.0c00781
Abstract: A carrier-based, immunogenic cell death (ICD)-eliciting platinum(IV) chemotherapeutic agent was synthesized via complexation between an axially derivatized Pt(IV)-tocopherol and hyaluronan-tocopherol nanocarrier. The resultant HA-Pt(IV) complex demonstrated anti-proliferative activity and induced calreticulin translocation, an indicator of… read more here.
Keywords: immunogenic cell; carrier based; based immunogenic; eliciting platinum ... See more keywords