A New Approach to Simplifying and Harmonizing Cancer Clinical Trials-Standardizing Eligibility Criteria.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.1664
Abstract: Importance Clinical trial sponsors rely on eligibility criteria to control the characteristics of patients in their studies, promote the safety of participants, and optimize the interpretation of results. However, in recent years, complex and often… read more here.
Keywords: cancer clinical; eligibility criteria; trial; clinical trials ... See more keywords
Improving Diversity in Clinical Trials by Using Real-world Data to Define Eligibility Criteria.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.7170
Abstract: This Viewpoint discusses the need for thoughtful, modernized eligibility criteria with equity prioritization in clinical trials. read more here.
Keywords: improving diversity; eligibility criteria; diversity clinical; clinical trials ... See more keywords
Changing recommendations for lung cancer screening: National Lung Cancer Roundtable member perspectives.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer"
DOI: 10.1002/cncr.34798
Abstract: The US Preventive Services Task Force (USPSTF) issued updated guidance for lung cancer screening using low‐dose computed tomography (LDCT) in March 2021, which expanded the eligibility criteria to include adults aged 50–80 years (previously 55–80)… read more here.
Keywords: lung cancer; eligibility criteria; cancer screening; national lung ... See more keywords
Assessing the Eligibility Criteria in Phase III Randomized Controlled Trials of Drug Therapy in Heart Failure With Preserved Ejection Fraction: The Critical Play-Off Between a "Pure" Patient Phenotype and the Generalizability of Trial Findings.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of cardiac failure"
DOI: 10.1016/j.cardfail.2017.04.006
Abstract: AIMS To investigate the effect of the different eligibility criteria used by phase III clinical studies in heart failure with preserved ejection fraction (HFpEF) on patient selection, phenotype, and survival. METHODS AND RESULTS We applied… read more here.
Keywords: failure; failure preserved; eligibility criteria; heart failure ... See more keywords
Prevalence and clinical implications of eligibility criteria for prolonged dual antithrombotic therapy in patients with PEGASUS and COMPASS phenotypes: Insights from the START-ANTIPLATELET registry.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2021.10.138
Abstract: AIM To analyze the prevalence and clinical implications of the eligibility criteria for prolonged dual antithrombotic therapy with ticagrelor 60 mg twice daily and/or rivaroxaban 2.5 mg twice daily in a contemporary real-world ACS registry. METHODS Patients… read more here.
Keywords: dual antithrombotic; eligibility criteria; eligibility; therapy ... See more keywords
Eligibility criteria for ambulatory colectomy.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of visceral surgery"
DOI: 10.1016/j.jviscsurg.2020.11.012
Abstract: PURPOSE OF THE STUDY To determine the statistical indicators aimed at identifying patients for whom ambulatory colectomy could be proposed without additional risk. PATIENTS AND METHODS The medical charts of patients who benefited from scheduled… read more here.
Keywords: eligibility criteria; age; eligibility; ambulatory colectomy ... See more keywords
OP173 Eligibility Criteria For “Accelerated Access” Approval: A Global Survey
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s0266462318001757
Abstract: Introduction: Several early access schemes (EAS) exist, which aim to accelerate patient access to new, potentially life-saving therapies. While some information exists on key schemes and their modalities, the determinants that drive adoption of a… read more here.
Keywords: eligibility criteria; early access; survey; percent ... See more keywords
The relationship between eligibility criteria and adverse events in randomized controlled trials of hematologic malignancies
Sign Up to like & getrecommendations! Published in 2017 at "Leukemia"
DOI: 10.1038/leu.2016.374
Abstract: To minimize adverse events (AEs) unrelated to drugs and maximize the likelihood of drug approvals, eligibility criteria for randomized controlled trials (RCTs) may be overly restrictive. The purpose of this study was to determine if… read more here.
Keywords: randomized controlled; eligibility criteria; eligibility; hematologic malignancies ... See more keywords
Towards clinical data-driven eligibility criteria optimization for interventional COVID-19 clinical trials
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Medical Informatics Association : JAMIA"
DOI: 10.1093/jamia/ocaa276
Abstract: Abstract Objective This research aims to evaluate the impact of eligibility criteria on recruitment and observable clinical outcomes of COVID-19 clinical trials using electronic health record (EHR) data. Materials and Methods On June 18, 2020,… read more here.
Keywords: eligibility criteria; covid clinical; eligibility; interventional covid ... See more keywords
Optimizing eligibility criteria and clinical trial conduct to enhance clinical trial participation for primary brain tumor patients.
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa015
Abstract: Building on an initiative to enhance clinical trial participation involving the Society for Neuro-Oncology (SNO), the Response Assessment in Neuro-Oncology (RANO) Working Group, patient advocacy groups, clinical trial cooperative groups, and other partners, we evaluate… read more here.
Keywords: clinical trial; trial; eligibility criteria; trial participation ... See more keywords
A2541 Hypertension Status among Chinese Adults Aged ≥ 50 years based on China-National Survey and SPRINT
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000549147.42807.3c
Abstract: Objectives: The Systolic Blood Pressure Intervention Trial (SPRINT) identified that a systolic blood pressure (SBP) target read more here.
Keywords: aged years; eligibility criteria; sprint; adults aged ... See more keywords