Photooxidation of 2,3-dihydroquinazolin-4(1H)-ones: retention or elimination of 2-substitution.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular diversity"
DOI: 10.1007/s11030-020-10174-3
Abstract: A series of mono and disubstituted 2,3-dihydroquinazolin-4(1H)-ones (DHQZs) were synthesized and the electronic and steric effects of the C2- and N3-substitutions on the retention or elimination of the C2-substitution by exposing them to the ultraviolet… read more here.
Keywords: retention elimination; elimination substitution; dihydroquinazolin ones;
How a Solvent Molecule Affects Competing Elimination and Substitution Dynamics. Insight into Mechanism Evolution with Increased Solvation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b04529
Abstract: Competiting SN2 substitution and E2 elimination reactions are of central importance in preparative organic synthesis. Here, we unravel how individual solvent molecules may affect underlying SN2/E2 atomistic dynamics, which remains largely unclear with respective to… read more here.
Keywords: molecule; elimination substitution; mechanism; solvent ... See more keywords