Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage
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DOI: 10.1038/srep40960
Abstract: The p53 tumour suppressor regulates the transcription initiation of selected genes by binding to specific DNA sequences at their promoters. Here we report a novel role of p53 in transcription elongation in human cells. Our… read more here.
Keywords: transcription elongation; p53; transcription; elongation blockage ... See more keywords