Genetic depletion of the RNA helicase DDX3 leads to impaired elongation of translating ribosomes triggering co-translational quality control of newly synthesized polypeptides
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DOI: 10.1093/nar/gkab667
Abstract: Abstract DDX3 is a multifaceted RNA helicase of the DEAD-box family that plays central roles in all aspects of RNA metabolism including translation initiation. Here, we provide evidence that the Leishmania DDX3 ortholog functions in… read more here.
Keywords: ddx3; rna helicase; elongation; translating ribosomes ... See more keywords