Cryo-EM structure of the fully assembled Elongator complex
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1232
Abstract: Abstract Transfer RNA (tRNA) molecules are essential to decode messenger RNA codons during protein synthesis. All known tRNAs are heavily modified at multiple positions through post-transcriptional addition of chemical groups. Modifications in the tRNA anticodons… read more here.
Keywords: structure; elongator complex; structure fully; cryo ... See more keywords
The Elongator complex regulates hypocotyl growth in darkness and during photomorphogenesis
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DOI: 10.1242/jcs.203927
Abstract: ABSTRACT The Elongator complex (hereafter Elongator) promotes RNA polymerase II-mediated transcript elongation through epigenetic activities such as histone acetylation. Elongator regulates growth, development, immune response and sensitivity to drought and abscisic acid. We demonstrate that… read more here.
Keywords: elongator; elongation; darkness; elongator complex ... See more keywords
Aspergillus fumigatus Elongator complex subunit 3 affects hyphal growth, adhesion and virulence through wobble uridine tRNA modification
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DOI: 10.1371/journal.ppat.1010976
Abstract: The eukaryotic multisubunit Elongator complex has been shown to perform multiple functions in transcriptional elongation, histone acetylation and tRNA modification. However, the Elongator complex plays different roles in different organisms, and the underlying mechanisms remain… read more here.
Keywords: growth; elongator; trna modification; elongator complex ... See more keywords
Architecture of the yeast Elongator complex
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DOI: 10.15252/embr.201643353
Abstract: The highly conserved eukaryotic Elongator complex performs specific chemical modifications on wobble base uridines of tRNAs, which are essential for proteome stability and homeostasis. The complex is formed by six individual subunits (Elp1‐6) that are… read more here.
Keywords: elongator; architecture yeast; yeast elongator; elongator complex ... See more keywords