Articles with "elucidation" as a keyword



Elucidation of mode of anticancerous activity of metal guanidinobenzimidazoles: A computational and experimental screening

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Published in 2024 at "Applied Organometallic Chemistry"

DOI: 10.1002/aoc.7654

Abstract: DNA‐binding agents often exhibits dual behavior of simultaneous binding with protein associated with cancerous cell development pathways. This simultaneous protein binding if contributed to malfunctioning of pro‐apoptotic proteins will reduce anticancerous potential of drugs. The… read more here.

Keywords: elucidation; cell; dna binding; dna ... See more keywords
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Structural elucidation of a series of benzamide derivatives

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Published in 2018 at "Magnetic Resonance in Chemistry"

DOI: 10.1002/mrc.4682

Abstract: Benzoic acid and its derivatives are compounds with significant benefits for human health, due to their biological and pharmacological properties, such as being antioxidant, anti‐inflammatory, anticancer, and neuroprotective. Benzoic compounds are present in human daily… read more here.

Keywords: elucidation; elucidation series; series benzamide; structural elucidation ... See more keywords

Complete Pathway Elucidation and Heterologous Reconstitution of Rhodiola Salidroside Biosynthesis.

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Published in 2018 at "Molecular plant"

DOI: 10.1016/j.molp.2017.12.007

Abstract: Salidroside is a bioactive tyrosine-derived phenolic natural product found in medicinal plants under the Rhodiola genus. In addition to their anti-fatigue and anti-anoxia roles in traditional medicine, Rhodiola total extract and salidroside have also displayed… read more here.

Keywords: hpaa; elucidation; rhodiola salidroside; rhodiola ... See more keywords

Synthesis of desmosine-containing cyclic peptide for the possible elucidation of elastin crosslinking structure

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Published in 2017 at "Tetrahedron"

DOI: 10.1016/j.tet.2017.05.045

Abstract: Abstract Elastin is a vital extracellular matrix protein, which is known for providing elasticity in numerous tissues. It is formed by the self-assembly and subsequent crosslinking of elastin precursor, tropoelastin. Two tetrafunctional, pyridinium-based amino acids… read more here.

Keywords: elucidation; elucidation elastin; cyclic peptide; containing cyclic ... See more keywords

Temperature-Controllable Liquid Crystalline Medium for Stereochemical Elucidation of Organic Compounds via Residual Chemical Shift Anisotropies.

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Published in 2024 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.3c04477

Abstract: The configuration elucidation of organic molecules continues to pose significant challenges in studies involving stereochemistry. Nuclear magnetic resonance (NMR) techniques are powerful for obtaining such structural information. Anisotropic NMR techniques, such as measurement of residual… read more here.

Keywords: chemical shift; shift anisotropies; residual chemical; elucidation ... See more keywords

Total Synthesis of an Immunogenic Trehalose Phospholipid from Salmonella Typhi and Elucidation of Its sn-Regiochemistry by Mass Spectrometry

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Published in 2019 at "Organic Letters"

DOI: 10.1021/acs.orglett.9b01725

Abstract: Diphosphatidyltrehalose (diPT) is an immunogenic glycolipid, recently isolated from Salmonella Typhi. Despite rigorous structure elucidation, the sn-position of the acyl chains on the glycerol backbone had not been unequivocally established. A stereoselective synthesis of diPT… read more here.

Keywords: salmonella typhi; elucidation; synthesis; mass spectrometry ... See more keywords

Design of an activatable NIR-II nanoprobe for the in vivo elucidation of Alzheimer's disease-related variations in methylglyoxal concentrations

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Published in 2022 at "Chemical Science"

DOI: 10.1039/d2sc05242c

Abstract: Clear elucidation of the changes in Alzheimer's disease (AD)-related methylglyoxal (MGO) levels in vivo is significant yet highly challenging. Fluorescence imaging in the second near-infrared region (NIR-II, 1000–1700 nm) has gained increasing attention as an… read more here.

Keywords: disease related; activatable nir; alzheimer disease; fluorescence ... See more keywords

Elucidation of flavonoids from potent Iranian Scutellaria species against Influenza A (H1N1) virus

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Published in 2023 at "Iranian Journal of Basic Medical Sciences"

DOI: 10.22038/ijbms.2022.66255.14553

Abstract: Objective(s): Influenza A virus (IAV) is a contagious illness. Different species of Scutellaria genus are used as a traditional remedy to reduce influenza symptoms. This study aimed to investigate the anti-influenza capacity of several species… read more here.

Keywords: glucoside; influenza; iranian scutellaria; virus ... See more keywords
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Multiscale Structural Elucidation of Peptide Nanotubes by X-Ray Scattering Methods

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Published in 2021 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2021.654339

Abstract: This mini-review presents the structural investigations of the self-assembled peptide nanotubes using X-ray scattering techniques. As compared to electron microscopy, scattering methods enable studies of nanotubes in solution under the appropriate physicochemical conditions and probe… read more here.

Keywords: elucidation; peptide nanotubes; scattering methods; ray scattering ... See more keywords

Metabolomics of various samples advancing biomarker discovery and pathogenesis elucidation for diabetic retinopathy

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Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.1037164

Abstract: Diabetic retinopathy (DR) is a universal microvascular complication of diabetes mellitus (DM), which is the main reason for global sight damage/loss in middle-aged and/or older people. Current clinical analyses, like hemoglobin A1c, possess some importance… read more here.

Keywords: retinopathy; various samples; metabolomics various; pathogenesis ... See more keywords

Abieta-7,13-Diene in Nematode-Infected Pinewood Pinus pinaster Branch Extracts: Isolation and the Elucidation and Characterization of Its Structure

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Published in 2025 at "Forests"

DOI: 10.3390/f16010061

Abstract: The oleoresin and volatile fraction produced by conifers, such as Pinus pinaster, play a crucial role in plant defence, acting as precursors to resin acids and adapting in response to environmental stress or pathogen attacks.… read more here.

Keywords: pinus pinaster; structure; elucidation; characterization ... See more keywords